Bioweapons: An Existential Threat?

March 6, 2017

With the rise and widespread dissemination of CRISPR technology, new concerns have been voiced over the possible applications of these technologies to the facile development of a new generation of potent biological weapons against which there would be no viable response.  I wrote about these threats in a recent issue of Frontline Security http://security.frontline....

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Shoddy drug research goes both ways

October 17, 2016

In the last few years there have been a striking number of claims of irreproducible pre-clinical pharma research. One of the most devastating was a 2012 report from Amgen researchers who were unable to reproduce the results of...

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crispr takes over

June 27, 2016

As new developments in science are introduced, they follow a familiar trajectory in the peer-reviewed literature of scientific journals. Starting from nothing, publications in hot areas grow in number year by year at an exponential rate, until all the low hanging fruit is picked, and eventual the...

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John Oliver takes on bad science

May 13, 2016

HBO comedian John Oliver has done a hilarious critique on how the media handles science reporting, and it's worth watching  (http://arste...

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Industrial Scale Genome Sequencing to Uncover Multifactorial Diseases

January 29, 2016

In my book on epigenetics, I discussed the problems of investigating diseases with a multifactorial basis, that is, conditions in which many genes determine a condition, such as cardiovascular disease. I argued that because a thousand or more genes may be involved, and each makes a small contribu...

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